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    Tearsolutions Inc.

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    Description

    • TearSolutions Inc. is a clinical stage Delaware Corporation based in Charlottesville, VA. The company is initiating a well powered 201 patient Phase II POC clinical trial for the treatment of the signs and symptoms of dry eye in primary Sjögrens Syndrome patients as an orphan indication (FPI June 2017, LPO Dec 2017). The trial will compare vehicle and two doses of LacripepTM, a novel 19 AA peptide that is present in normal tears and deficient in all forms of dry eye. The peptide restores homeostasis to the ocular surface, in particular the barrier function of the corneal epithelium and normal function of sensory nerves at the corneal surface in Aire (-/-) dry eye mice with preexisting disease. Restoration of epithelial barrier function can be measured clinically as a decrease in corneal fluorescein staining while the improvement in sensory nerve function restores normal production of the components of tears: the aqueous via reinnervation of lacrimal glands, the lipid via reinnervation of meibomium glands and the mucin via reinnervation of goblet cells. Improvement in fluorescein staining and tear production (Schirmer tear test) are clinical signs of dry eye that have been used in the FDA approval of Xiidra and Restasis respectively.LacripepTM was discovered as a naturally occurring fragment of the larger 119 AA protein, lacritin, in an unbiased screen for novel factors capable of addressing dry eye.Management team- CEO/President: Thomas Gadek PhD- Executive Chairman/Cofounder: Mark B. Logan- CSO/Cofounder: Gordon W. Laurie PhD, FARVO- CTO: John C. Moore- CFO: Colin M. Rolph- Regulatory and Clinical: Michelle Carpenter JD, RAC- Medical Director: Marc G. Odrich, MD- Secretary: Mac Thompson, LLDAdvisory Board- Manus C. Kraff MD- Jae K. Lee PhD- J. Daniel Nelson MD, FACS, FARVO- Kazuo Tsubota MD, FARVOGust (https://gust.com/companies/tearsolutions-Inc)
    • location

      Headquarters:315 Old Ivy Way Suite 301, Charlottesville, Virginia, United States

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    • Tearsolutions Inc. phone

      Phone Number: +1 434-227-2145

    • Tearsolutions Inc. website

      Website: https://www.tearsolutions.com

    • Tearsolutions Inc. employees

      Employees:5

    • Tearsolutions Inc. revenue

      Revenue:$1 - 10M

    • Tearsolutions Inc. legal name

      Legal Name:Tearsolutions Inc.

    • Tearsolutions Inc.'s Social Media

      Tearsolutions Inc. linkedin Tearsolutions Inc. facebook
    • done Is this data correct?

    • |  NAICS Code: 561990  |

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    Person level website identification

    CEO for Tearsolutions Inc.

    Mark Logan

    Chief Executive Officer And President And Cofounder

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    View Employees

    Gordon Laurie

    Co-Founder

    Frequently Asked Questions regarding Tearsolutions Inc.

    • Where are Tearsolutions Inc.'s Headquarters?

      Tearsolutions Inc.'s Headquarters are in 315 Old Ivy Way Suite 301,Charlottesville,Virginia,United States

    • What is Tearsolutions Inc.'s phone number?

      Tearsolutions Inc.'s phone number is +1 434-227-2145

    • What is Tearsolutions Inc.'s official website?

      Tearsolutions Inc.'s official website is https://www.tearsolutions.com

    • What is Tearsolutions Inc.'s Revenue?

      Tearsolutions Inc.'s revenue is $1 - 10M

    • What is Tearsolutions Inc.'s NAICS code?

      Tearsolutions Inc.'s NAICS code is 561990

    • How many employees are working in Tearsolutions Inc.

      Tearsolutions Inc. has 5 employees

    • What is Tearsolutions Inc.'s Industry?

      Tearsolutions Inc. is in the industry of Pharmaceuticals

    • Who is Tearsolutions Inc.'s CEO?

      Tearsolutions Inc.'s CEO is Mark Logan

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