Abzyme Therapeutics

Description

• Abzyme Therapeutics is a leading provider of recombinant antibody development, modification and production services. The company is located in the Eastern Pennsylvania biotechnology/pharmaceutical hub 30-miles west of Philadelphia.In immunized animals, somatic hypermutation plays a leading role in antibody maturation by generating point mutations in the V genes, which provides high-affinity antibodies required for the affinity maturation process. Abzyme Therapeutics LLC developed yeast-based technology platforms mimicking mammalian antibody diversification and affinity maturation processes. As this is an animal-free in vitro system, we are able to develop antibodies not only to conventional targets but also to a variety of difficult targets including non-immunogenic and highly toxic antigens or cell surface antigens.Unique to Abzyme is our proprietary eukaryotic in vitro antibody discovery/optimization platform based on yeast display self-diversifying libraries, rapid target-directed antibody maturation, and a FACS single cell sorting approach to identify desired antibodies. These combined technologies enable Abzyme Therapeutics to shorten typical monoclonal antibody development/optimization times from 4.5 6 months to 6 10 weeks. Abzymes antibody discovery platform incorporates the ability to select for key properties such as epitopic diversity, binding affinity, expressibility, solubility, developability, broad-reactivity and target-specificity into real-time screening.Within our focus of providing services in antibody discovery and engineering, Abzyme is pursuing additional select, strategic partnerships, to further leverage our powerful Triple-mode Antibody Discovery platform with proprietary antibody libraries and Abz2 Bispecifics Technology. Through the plug-and-play process, an existing IgG traditional antibody can be rapidly transformed into well-expressing Abz2 bispecifics with a completely normal IgG structure.
• 

  Headquarters:321 Jones Boulevard Suite 300, Royersford, Pennsylvania, United States

  More
• 

  Phone Number: +1 610-990-7531

• 

  Website: https://www.abzymetx.com

• 

  Employees:9

• 

  Revenue:$10 - 50M

• 

  Legal Name:Abzyme Therapeutics

• Abzyme Therapeutics's Social Media

  
• Is this data correct?

• |  NAICS Code: 238990  |

  Show More